Allostery

Biology is never still. Proteins bend, shift, and respond to their surroundings—yet today’s leading AI models largely capture them as static structures. Allostery is building a new generation of foundation models that unite artificial intelligence with quantum physics to understand molecules in motion.

Its platform combines 3D structure prediction, neural force fields, and generative AI to model molecular interactions, energy landscapes, and conformational dynamics. By grounding its predictions in physics, Allostery aims to reveal the mechanisms behind complex biology and design molecules that remain viable beyond the limits of existing training data.

This deeper understanding could open new paths to previously elusive targets, from molecular glues and disordered proteins to membrane proteins and advanced therapeutics. Allostery’s vision is to make the atomic world as understandable—and ultimately as programmable—as software.